Steroidal glycoside structure

Botany
Talong is a coarse, usually branched, prickly or unarmed, erect, half-woody plant, growing to a height of to 1 meter. Leaves are ovate to oblong-ovate, 10 to 25 centimeters long, stellate-hairy beneath, and irregularly or shallowly lobed at the margins. Flowers are axillary, purplish, about centimeters long. Fruit is fleshy, smooth, purple, up to 25 centimeters long, extremely variable in shape, round, oblong, or cylindric-oblong.

Distribution
- Cultivated throughout the Philippines for the edible fruit; the elongated variety, the most cultivated.
- Nowhere spontaneous.
- Cultivated in all warm countries.

NSAIDS have antipyretic activity and can be used to treat fever. [75] [76] Fever is caused by elevated levels of prostaglandin E2 , which alters the firing rate of neurons within the hypothalamus that control thermoregulation. [75] [77] Antipyretics work by inhibiting the enzyme COX, which causes the general inhibition of prostanoid biosynthesis ( PGE2 ) within the hypothalamus . [75] [76] PGE2 signals to the hypothalamus to increase the body's thermal set point. [76] [78] Ibuprofen has been shown more effective as an antipyretic than paracetamol (acetaminophen). [77] [79] Arachidonic acid is the precursor substrate for cyclooxygenase leading to the production of prostaglandins F, D & E.

Steroidal glycoside structure

steroidal glycoside structure

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