"Performance-enhancing drugs" (PED's) is used as an umbrella term to refer to substances and supplements that boost athletic performance. Types of performance-enhancing drugs include anabolic steroids, androstenedione, human growth hormone, erythropoietin, diuretics, creatine and stimulants—most of which are illegal and carry serious health risks.
Erythropoietin (EPO), used to boost aerobic capacity by increasing the number of red blood cells in the bloodstream (blood-doping), was banned by the International Olympic Commission in 1985 and outlawed in 1986, but has come under fire in recent years throughout the running and cycling worlds.
Drug testing is rare in ultras except at world championships and races like Ultra-Trail du Mont-Blanc and at International Skyrunning Federation events. The International Association of Ultrarunners (IAU) implements doping controls at the 24-Hour, 50k Road, 100k Road, and Trail World Championships . Stateside testing takes place as well, but less frequently. Richard Bolt , an executive committee member for the USA Track and Field Mountain/Ultra/Trail (MUT) Council explains, “The Pikes Peak Ascent in Colorado conducted testing in 2010 and 2014 when it was the World Long Distance Mountain Running Challenge . Out-of-competition testing occurs on . soil for . athletes who have performed well at World Mountain Running Association (WMRA) and IAU Championships.”
In sports, the phrase performance-enhancing drugs is popularly used in reference to anabolic steroids or their precursors (hence the colloquial term "steroids"); anti-doping organizations apply the term broadly.  There are agencies such as WADA and USADA that try to prevent athletes from using these drugs by performing drug tests. WADA was founded on November 10, 1999 by Dick Pound . The World Anti-doping Agency focuses on establishing and enforcing rules and codes of all sports around the world. Their goal is to make all sports played fairly between all athletes in a doping free organization with the power to prevent athletes from using any form of performance-enhancing drugs. USADA started October 1, 2000 as non-profit and was composed of nine members. Five of which were former Olympic athletes with the other four elected from independent companies. This is the United States Anti-doping Agency and have the ability to test athletes across the nation. Steroids and performance-enhancing drugs are used across all sports organizations around the world.