G6PD is a genetic disorder affecting the red blood cells. In the affected person the defect is found in an enzyme called Glucose -6-phosphate dehydogenase. Deficiency of this enzyme causes premature breakdown of red blood cells leading to hemolysis. Hemolytic anemia is the most common problem caused due to G6PD. In hemolytic anemia, red blood cells are destroyed faster than they are produced. In people suffering from G6PD deficiency, hemolytic anemia is often triggered as a result of bacterial infection or viral infection. Certain drugs are also known to cause hemolytic anemia. Antimalarial drugs, antibiotics, etc are the main. Hemolytic anemia can also occur in a person who has eaten Fava beans and who is having G6PD deficiency. There are several reasons for fluctuation of platelet, but before that let me know the full medical history if you are suffering from any illness.
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Unfortunately cancer doesn't follow many rules about how it responds to things. My second rottie B'Elanna had paraneoplastic syndrome with immune-mediated hemolytic anemia, a very similar condition. We thought she just had IMHA until her stomach literally fell apart. She responded to treatment (she was on prednisolone, azathioprine, doxycycline, and azithromycin for suspected Bartonella infection) slowly for about a month, then just crashed and burned. We thought it was a perforated ulcer due to the pred, but the surgeon said her whole stomach was very friable, and biopsy results which came up a week after she died said she had cancer. We tried to get her stomach back together, but she had post-surgery complications (pulmonary thromboembolism, probably stomach fell apart again), so I had to euthanize her.